Decoration of trastuzumab with short oligonucleotides: synthesis and detailed characterization
Author:
Affiliation:
1. Department of Organic and Macromolecular Chemistry
2. Ghent University
3. 9000 Ghent
4. Belgium
5. BAM Federal Institute for Materials Research and Testing
6. Department of Analytical Chemistry; Reference Materials
7. 12489 Berlin
8. Germany
Abstract
Trastuzumab, an antibody prescribed for the treatment of metastatic breast cancer, was covalently conjugated to oligonucleotides and characterized by high resolution MALDI-ToF MS.
Funder
H2020 Marie Skłodowska-Curie Actions
Universiteit Gent
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB02216F
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