Tuning the relaxation rates of dual-mode T1/T2 nanoparticle contrast agents: a study into the ideal system

Author:

Keasberry Natasha A.123,Bañobre-López Manuel45,Wood Christopher123,Stasiuk Graeme. J.12367,Gallo Juan12345,Long Nicholas. J.12389

Affiliation:

1. Department of Chemistry

2. Imperial College London

3. London, UK

4. International Iberian Nanotechnology Laboratory (INL)

5. 4715-330 Braga, Portugal

6. School of Biological

7. Biomedical and Environmental Sciences

8. Comprehensive Cancer Imaging Centre

9. Department of Surgery & Cancer

Abstract

Combination of a paramagnetic metal and a magnetic nanoparticle, and the effects on MR relaxivity properties, has led to the preparation of nanoparticles with unmatched potential for MRI.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Reference47 articles.

1. Molecular Imaging in Cancer

2. Emerging concepts in molecular MRI

3. D. Weishaupt , V. D.Kochli and B.Marincek , How Does MRI Work?: An introduction to the Physics and Function of Magnetic Resonance Imaging , Springer , 2nd edn, 2006

4. Inorganic nanoparticle-based T1 and T1/T2 magnetic resonance contrast probes

5. Gd-containing conjugated polymer nanoparticles: bimodal nanoparticles for fluorescence and MRI imaging

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