Emerging nanobiotechnology-encoded relaxation tuning establishes new MRI modes to localize, monitor and predict diseases

Author:

Wang Taixia12,Zhang Xueni1,Xu Yuan1ORCID,Xu Yingchun1,Zhang Yifeng12,Zhang Kun12ORCID

Affiliation:

1. Central Laboratory and Ultrasound Research and Education Institute, Shanghai Tenth People's Hospital, Tongji University School of Medicine, No. 301 Yan-chang-zhong Road, Shanghai 200072, China

2. Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment, National Clinical Research Center for Interventional Medicine, Tongji University School of Medicine, No. 301 Yan-chang-zhong Road, Shanghai 200072, China

Abstract

Tumor microenvironment-activated longitudinal or transverse relaxation tuning shows highly promising applications. Smart MRI contrast agents exhibit high potential for tracking cancer progression and evolution and monitoring treatment process.

Funder

National Natural Science Foundation of China

Science and Technology Commission of Shanghai Municipality

Shanghai Rising-Star Program

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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