Cross-kingdom regulation by dietary plant miRNAs: an evidence-based review with recent updates

Author:

Jia MingXi12,He JinTao1,Bai WeiDong2,Lin QinLu1,Deng Jing1,Li Wen1ORCID,Bai Jie1,Fu Da13,Ma YuShui3,Ren JiaLi1,Xiong ShouYao4

Affiliation:

1. National Engineering Laboratory for Deep Process of Rice and Byproducts, Hunan Province Key Laboratory of Edible forestry Resources Safety and Processing Utilization, College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, Hunan, China

2. College of Light Industry and Food Sciences, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, Guangdong, China

3. Central Laboratory for Medical Research, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China

4. College of Mathematics and Statistics, Changsha University of Science and Technology, Changsha 410114, China

Abstract

This study summarizes the mechanism by which plant-derived miRNAs remain stable and are absorbed in mammals, and reviews the updated evidence regarding the therapeutic potential of plant miRNAs’ cross-kingdom activity.

Funder

Natural Science Foundation of Hunan Province

Science and Technology Program of Hunan Province

Central South University of Forestry and Technology

Education Department of Hunan Province

Double First Class University Plan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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