Resin-free peptide synthesis mediated by tri(4-benzoylphenyl) phosphate (TBP) derivatives as small-molecule supports
Author:
Affiliation:
1. Shaanxi Key Laboratory of Polymer Science & Technology
2. OME Key Laboratory of Supernormal Material Physics & Chemistry
3. School of Chemistry and Chemical Engineering
4. Northwestern Polytechnical University
5. Xi'an
Abstract
A series of novel tri(4-benzoylphenyl) phosphate (TBP) derivatives with unique precipitation-inducing properties were synthesized and used as C-terminal protecting groups of amino acids and recyclable supports in peptide synthesis.
Funder
National Natural Science Foundation of China
Northwestern Polytechnical University
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/QO/C9QO01480B
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