Mild and efficient synthesis of benzothiazolopyrimidine derivatives<i>via</i>CuAAC/ring cleavage/cyclization reaction-Reference-Cited by-同舟云学术

Mild and efficient synthesis of benzothiazolopyrimidine derivativesviaCuAAC/ring cleavage/cyclization reaction

Published:2023 Issue:33 Volume:13 Page:22966-22972
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yang Weiguang¹²^ORCID,Luo Danyang¹,Li Guanrong¹,Hu Weigao¹,Zheng Jia¹,Chen Lanmei¹

Affiliation:

1. Key Laboratory of Big Data Mining and Precision Drug Design of Guangdong Medical University, The Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, 524023, China

2. GuangDong Engineering Technology Research Center for the Development and Utilization of Mangrove Wetland Medicinal Resources, The Marine Biomedical Research Institute of Guangdong Zhanjiang, Zhanjiang, Guangdong, 524023, China

Abstract

Three-component one-pot synthesis of benzothiazolopyrimidine derivatives through a CuAAC/ring cleavage/cyclization process.

Funder

Guangdong Medical Research Foundation

Science and Technology Planning Project of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA04082H

Reference37 articles.

1. Benz-fused mesoionic xanthine analogs as inhibitors of cyclic-AMP phosphodiesterase

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3. Structure-activity relationship study of antimalarial indolo [2,1-b]quinazoline-6,12-diones (tryptanthrins). Three dimensional pharmacophore modeling and identification of new antimalarial candidates

4. Diastereo‐ and Enantioselective Mannich/Cyclization Cascade Reaction Access to Chiral Benzothiazolopyrimidine Derivatives

5. Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2