All-in-one detection of breast cancer-derived exosomal miRNA on a pen-based paper chip

Author:

Guo Song1,Xie Han2,Zhao Xudong2,He Honghao3,Feng Xiaojun2ORCID,Li Yiwei2ORCID,Liu Bi-Feng2ORCID,Chen Peng2ORCID

Affiliation:

1. Department of Anesthesiology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong 510317, China

2. The Key Laboratory for Biomedical Photonics of MOE at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Systems Biology Theme, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China

3. Sino-US Telemed (Wuhan) Co., Ltd, China

Abstract

An all-in-one detection strategy was proposed for the identification of breast cancer-derived exosomal miRNA-21, exhibiting high sensitivity and specificity on a pen-based paper chip.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

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