Spatially resolved single-molecule profiling of microRNAs in migrating cells driven by microconfinement-Reference-Cited by-同舟云学术

Spatially resolved single-molecule profiling of microRNAs in migrating cells driven by microconfinement

Published:2022 Issue:37 Volume:13 Page:11197-11204
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Fan Zihui¹,Li Bin¹,Wang Ya-Jun¹,Huang Xuedong¹,Li Binxiao¹,Wang Shurong¹,Liu Yixin¹,Liu Yan-Jun¹^ORCID,Liu Baohong¹^ORCID

Affiliation:

1. Institutes of Biomedical Sciences, Shanghai Stomatological Hospital, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Chemistry, State Key Lab of Molecular Engineering of Polymers, Fudan University, Shanghai 200438, China

Abstract

Spatially resolved profiling of miRNAs was realized in migrating cells using enzyme-free signal-amplification nanoprobes, in which distinct migration modes of single living cells are driven by precisely engineered microchips.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC04132D

Reference47 articles.

1. Focal Adhesion–Independent Cell Migration

2. Cancer Cells Invade Confined Microchannels via a Self-Directed Mesenchymal-to-Amoeboid Transition

3. Dynamic imaging of cancer growth and invasion: a modified skin-fold chamber model