Gene delivery polymer structure–function relationships elucidated via principal component analysis
Author:
Affiliation:
1. The Johns Hopkins University School of Medicine
2. Department of Biomedical Engineering
3. Translational Tissue Engineering Center
4. Baltimore MD
5. USA
6. The Johns Hopkins University
7. Department of Materials Science and Engineering
Abstract
Principal component analysis was applied to a biomaterial library of poly(beta-amino ester)s, useful for non-viral gene delivery, to elucidate chemical parameters that drive biological function.
Funder
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC04417K
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