Machine learning guided structure function predictions enable in silico nanoparticle screening for polymeric gene delivery

Author:

Gong DennisORCID,Ben-Akiva ElanaORCID,Singh Arshdeep,Yamagata HannahORCID,Est-Witte SavannahORCID,Shade Julie K.,Trayanova Natalia A.ORCID,Green Jordan J.ORCID

Publisher

Elsevier BV

Subject

Molecular Biology,Biomedical Engineering,Biochemistry,Biomaterials,General Medicine,Biotechnology

Reference48 articles.

1. The once and future gene therapy;Bulaklak;Nat. Commun.,2020

2. Recent advances in the development of gene delivery systems;Sung;Biomater. Res.,2019

3. Toward gene transfer nanoparticles as therapeutics;Kavanagh;Adv. Healthc. Mater.,2022

4. Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors;Boutin;Hum. Gene Ther.,2010

5. Role of lipid-based and polymer-based non-viral vectors in nucleic acid delivery for next-generation gene therapy;Wahane;Molecules,2020

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