Feature engineering applied to intraoperativein vivoRaman spectroscopy sheds light on molecular processes in brain cancer: a retrospective study of 65 patients-Reference-Cited by-同舟云学术

Feature engineering applied to intraoperativein vivoRaman spectroscopy sheds light on molecular processes in brain cancer: a retrospective study of 65 patients

Published:2019 Issue:22 Volume:144 Page:6517-6532
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Lemoine Émile¹²³⁴⁵^ORCID,Dallaire Frédérick⁵³⁴⁶²,Yadav Rajeev⁷³⁴^ORCID,Agarwal Rajeev⁷³⁴,Kadoury Samuel⁶²³⁴,Trudel Dominique⁵³⁴,Guiot Marie-Christine⁸⁹¹⁰¹¹³,Petrecca Kevin⁸⁹¹⁰¹¹³,Leblond Frédéric¹²³⁴⁵

Affiliation:

1. Department of Engineering Physics

2. Polytechnique Montreal

3. Montreal

4. Canada

5. Centre de Recherche du Centre Hospitalier de l'Université de Montréal

6. Department of Computer and Software Engineering

7. ODS Medical Inc.

8. Brain Tumour Research Center

9. Montreal Neurological Institute and Hospital

10. Department of Neurology and Neurosurgery

11. McGill University

Abstract

A new method to improve the statistical interpretability of biological Raman Spectroscopy was applied to spectra acquiredin vivoduring neurosurgical resection of brain cancer, revealing oncogenic processes captured by the Raman system.

Funder

Natural Sciences and Engineering Research Council of Canada

Canadian Institutes of Health Research

Canada First Research Excellence Fund

Mitacs

Fonds de Recherche du Québec - Santé

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/AN/C9AN01144G