Iron-catalyzed cross-electrophile coupling of bromostyrenes and chlorosilanes

Author:

Lin Ying12,Zou Liang12,Bai Renren12,Ye Xiang-Yang12ORCID,Xie Tian12,Ye Yang12ORCID

Affiliation:

1. School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, PR China

2. Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang 311121, PR China

Abstract

An efficient Fe-catalyzed cross-electrophile vinyl silylation protocol is reported for the first time. A set of 1,4-diene silanes are conveniently synthesized from simple vinyl chlorosilanes and alkenyl bromides under mild reductive conditions.

Funder

Department of Health of Zhejiang Province

Hangzhou Normal University

Ministry of Science and Technology of the People's Republic of China

Science and Technology Department of Zhejiang Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference74 articles.

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4. Synthesis of Vinylsilanes

5. Rh(I)-Catalyzed Silylation of Aryl and Alkenyl Cyanides Involving the Cleavage of C−C and Si−Si Bonds

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