An ICT-guided ratiometric naphthalene–benzothiazole-based probe for the detection of cyanide with real-time applications in human breast cancer cells

Author:

Banerjee Shilpita1,Mandal Moumi1,Halder Satyajit2,Karak Anirban1,Banik Dipanjan1,Jana Kuladip2,Mahapatra Ajit Kumar1ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711 103, India

2. Division of Molecular Medicine, Bose Institute, P 1/12, CIT Scheme VIIM, Kolkata-700 054, India

Abstract

The probe MNBTZ reacts with cyanide by inhibiting ICT and resulting in a ratiometric fluorescence change from bright yellow to light purple. The hypsochromic shift in wavelength can be seen in the human breast cancer cell imaging study.

Funder

Council of Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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