Sources of biases in the <i>in vitro</i> testing of nanomaterials: the role of the biomolecular corona-Reference-Cited by-同舟云学术

Sources of biases in the in vitro testing of nanomaterials: the role of the biomolecular corona

Published:2024 Issue:5 Volume:9 Page:799-816
ISSN:2055-6756
Container-title:Nanoscale Horizons
language:en
Short-container-title:Nanoscale Horiz.

Author:

Castagnola Valentina¹²^ORCID,Tomati Valeria³,Boselli Luca⁴^ORCID,Braccia Clarissa⁵,Decherchi Sergio⁶^ORCID,Pompa Pier Paolo⁴^ORCID,Pedemonte Nicoletta³,Benfenati Fabio¹²^ORCID,Armirotti Andrea⁵

Affiliation:

1. Center for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Largo Rosanna Benzi 10, 16132 Genova, Italy

2. IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi 10, 16132 Genova, Italy

3. UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Via Gaslini 5, 16147 Genova, Italy

4. Nanobiointeractions & Nanodiagnostics, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy

5. Analytical Chemistry Facility, Istituto Italiano di Tecnologia, Via Morego 30, Genova, 16163, Italy

6. Data Science and Computation Facility, Istituto Italiano di Tecnologia, via Morego, 30, Genova, 16163, Italy

Abstract

A comparative journey into biomolecular corona features involving proteomics, lipidomics, high throughput in vitro screening, and molecular feature analysis to investigate the in vivo/in vitro bias for nanomaterials testing in biology.

Funder

Ministero della Salute

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NH/D3NH00510K

Reference104 articles.

1. Biomolecular coronas provide the biological identity of nanosized materials

2. A Decade of the Protein Corona

3. Inorganic nanoparticle biomolecular corona: formation, evolution and biological impact

4. Identification of Receptor Binding to the Biomolecular Corona of Nanoparticles

5. The nanoparticle biomolecule corona: lessons learned – challenge accepted?

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