Sequential Sonogashira/intramolecular aminopalladation/cross-coupling of ortho-ethynyl-anilines catalyzed by a single palladium source: rapid access to 2,3-diarylindoles-Reference-Cited by-同舟云学术

Sequential Sonogashira/intramolecular aminopalladation/cross-coupling of ortho-ethynyl-anilines catalyzed by a single palladium source: rapid access to 2,3-diarylindoles

Published:2021 Issue:6 Volume:19 Page:1329-1333
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wang Jiwei¹²³⁴⁵,Wang Gendi⁶⁷⁸⁹¹⁰,Cheng Xiang⁶⁷⁸⁹¹⁰,Liu Ye¹²³⁴⁵^ORCID,Zhang Jun⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Shanghai Key Laboratory of Green Chemistry and Chemical Processes

2. School of Chemistry & Molecular Engineering

3. East China Normal University

4. Shanghai 200062

5. China

6. Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering

7. Feringa Nobel Prize Scientist Joint Research Center

8. School of Chemistry and Molecular Engineering

9. East China University of Science and Technology

10. Shanghai 200237

Abstract

An efficient one-pot protocol for the synthesis of 2,3-diarylindoles via Pd-catalyzed bis-arylative cyclization of o-ethynylanilines is reported. The present methodology exhibits a broad substrate scope, producing various 2,3-diaryl indoles.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB02295K

Reference43 articles.

1. Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

2. Fate of 3,3‘-Diindolylmethane in Cultured MCF-7 Human Breast Cancer Cells

3. Constituents of Trigonostemon chinensis

4. Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety

5. Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

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