Palladium-catalyzed highly chemoselective dearomative spirocyclization of Ugi adducts: facile access to functionalized benzoazepinespiroindolenines with diastereoselectivity-Reference-Cited by-同舟云学术

Palladium-catalyzed highly chemoselective dearomative spirocyclization of Ugi adducts: facile access to functionalized benzoazepinespiroindolenines with diastereoselectivity

Published:2023 Issue:20 Volume:10 Page:5083-5091
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Qu Chuan-Hua¹^ORCID,Li Shu-Ting¹,Liu Jian-Bo¹,Tang Dian-Yong¹^ORCID,Xu Zhi-Gang¹,Chen Zhong-Zhu¹,Song Gui-Ting¹

Affiliation:

1. College of Pharmacy, National & Local Joint Engineering Research center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing University of Arts and Sciences, Chongqing 402160, China

Abstract

The development of chemoselective strategies for complex molecules is intrinsically challenging. In this paper, a facile and diversity-oriented access to benzoazepinespiroindolenines is elaborated via Pd-catalyzed highly chemoselective dearomative spirocyclization of Ugi adducts.

Funder

National Natural Science Foundation of China

Chongqing Municipal Education Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO01262J

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