A simple and fast protocol for the synthesis of 2-amino-4-(4-formylphenyl)-4H-chromene-3-carbonitrile to develop an optical immunoassay for the quantification of botulinum neurotoxin type F-Reference-Cited by-同舟云学术

A simple and fast protocol for the synthesis of 2-amino-4-(4-formylphenyl)-4H-chromene-3-carbonitrile to develop an optical immunoassay for the quantification of botulinum neurotoxin type F

Published:2020 Issue:46 Volume:44 Page:20083-20091
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Shenbagavalli Kathiravan¹²³⁴,Yadav Shiv Kumar⁵⁶⁴,Ananthappan Periyasamy¹²³⁴,Sundaram Ellairaja⁷⁸⁹⁴,Ponmariappan Sarkaraisamy⁵⁶⁴,Vasantha Vairathevar Sivasamy¹²³⁴^ORCID

Affiliation:

1. Department of Natural Products Chemistry

2. School of Chemistry

3. Madurai 625 021

4. India

5. Defence Research and Development Establishment

6. Gwalior-474 002

7. Department of Chemistry

8. Vivekanada College Tiruvedakam West

9. Madurai 625 234

Abstract

In this study, a novel optical immunoassay platform using (S)-2-amino-4-(4-formylphenyl)-4H-chromene-3-carbonitrile, which was synthesized by an ultra-sonication method, as an optical probe.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ04103C

Reference66 articles.

1. Centrifugal Microfluidic Platform for Ultrasensitive Detection of Botulinum Toxin

2. Laboratory Diagnostics of Botulism

3. Light Chain Diversity among the Botulinum Neurotoxins

4. A Simple, Rapid and Sensitive FRET Assay for Botulinum Neurotoxin Serotype B Detection

5. Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity

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