Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity-Reference-Cited by-同舟云学术

Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity

Published:2015-02-17 Issue:1 Volume:6 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Matsumura Takuhiro,Sugawara Yo,Yutani Masahiro,Amatsu Sho,Yagita Hideo,Kohda Tomoko,Fukuoka Shin-Ichi,Nakamura Yutaka,Fukuda Shinji,Hase Koji,Ohno Hiroshi,Fujinaga Yukako

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms7255.pdf

Reference38 articles.

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2. Sakaguchi, G. Clostridium botulinum toxins. Pharmacol. Ther. 19, 165–194 (1982).

3. Amatsu, S., Sugawara, Y., Matsumura, T., Kitadokoro, K. & Fujinaga, Y. Crystal structure of Clostridium botulinum whole hemagglutinin reveals a huge triskelion-shaped molecular complex. J. Biol. Chem. 288, 35617–35625 (2013).

4. Fujinaga, Y. et al. Identification and characterization of functional subunits of Clostridium botulinum type A progenitor toxin involved in binding to intestinal microvilli and erythrocytes. FEBS Lett. 467, 179–183 (2000).

5. Gu, S. et al. Botulinum neurotoxin is shielded by NTNHA in an interlocked complex. Science 335, 977–981 (2012).

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