Tropisetron modulates peripheral and central serotonin/insulin levels via insulin and nuclear factor kappa B/receptor for advanced glycation end products signalling to regulate type-2 diabetes in rats-Reference-Cited by-同舟云学术

Tropisetron modulates peripheral and central serotonin/insulin levels via insulin and nuclear factor kappa B/receptor for advanced glycation end products signalling to regulate type-2 diabetes in rats

Published:2018 Issue:22 Volume:8 Page:11908-11920
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mohamed Reem Ali¹²³⁴⁵^ORCID,Galal Omneya¹²³⁴⁵,Mohammed Ahmed Refaat¹²³⁴⁵,El-Abhar Hanan Salah¹²⁶⁵

Affiliation:

1. Department of Pharmacology and Toxicology

2. Faculty of Pharmacy

3. October University for Modern Sciences and Arts (MSA)

4. 6th October City

5. Egypt

6. Cairo University

Abstract

Schematic illustration of tropisetron's (5-HT3 antagonist) modulation of the insulin and Wnt/β-catenin signaling pathways both peripherally and centrally in type 2 diabetes.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C7RA13105D

Reference79 articles.

1. Robbins and Cotran Pathologic Basis of Disease: 7th Edition

2. Diabetes in Sub-Saharan Africa: Kenya, Mali, Mozambique, Nigeria, South Africa and Zambia

3. Diagnosis and Classification of Diabetes Mellitus

4. Type 2 diabetes as an inflammatory disease

5. β-Cell Glucose Toxicity, Lipotoxicity, and Chronic Oxidative Stress in Type 2 Diabetes

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