Palladium(ii) complexes with thiosemicarbazones derived from pyrene as topoisomerase IB inhibitors-Reference-Cited by-同舟云学术

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Palladium(ii) complexes with thiosemicarbazones derived from pyrene as topoisomerase IB inhibitors

Published:2019 Issue:44 Volume:48 Page:16509-16517
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Oliveira Carolina G.¹²³⁴⁵^ORCID,Romero-Canelón Isolda⁶⁷⁸⁹¹⁰^ORCID,Silva Monize M.⁶¹¹³⁴,Coverdale James P. C.⁶¹¹³⁴^ORCID,Maia Pedro Ivo S.⁶¹²¹³⁴,Batista Alzir A.⁶¹¹³⁴^ORCID,Castelli Silvia¹⁴¹⁵¹⁶¹⁷,Desideri Alessandro¹⁴¹⁵¹⁶¹⁷,Sadler Peter J.⁶⁷⁸⁹^ORCID,Deflon Victor M.¹²³⁴^ORCID

Affiliation:

1. São Carlos Institute of Chemistry

2. University of São Paulo

3. São Carlos

4. Brazil

5. Institute of Chemistry

6. Department of Chemistry

7. University of Warwick

8. Coventry

9. UK

10. School of Pharmacy

11. Federal University of São Carlos

12. Federal University of the Triângulo Mineiro

13. Uberaba

14. Department of Biology

15. University of Rome Tor Vergata

16. Rome

17. Italy

Abstract

New palladium complexes exhibit potent antiproliferative activity against A2780 and cisplatin-resistant A2780C is human ovarian cancer cells.

Funder

Engineering and Physical Sciences Research Council

Wellcome Trust

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de Minas Gerais

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/DT/C9DT02570G

Reference51 articles.

1. Manganese(II) complexes with thiosemicarbazones as potential anti-Mycobacterium tuberculosis agents

2. Novel Zinc(II) Complexes [Zn(atc-Et)2] and [Zn(atc-Ph)2]: In Vitro and in Vivo Antiproliferative Studies

3. Neuroprotective Activity of 3-Aminopyridine-2-Carboxaldehyde Thiosemicarbazone (PAN-811), a Cancer Therapeutic Agent

4. Tumor Cell Death Induced by Topoisomerase-Targeting Drugs

5. The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα

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