Solid-state landscape and biopharmaceutical implications of novel metformin-based salts-Reference-Cited by-同舟云学术

Solid-state landscape and biopharmaceutical implications of novel metformin-based salts

Published:2022 Issue:28 Volume:46 Page:13725-13737
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Diniz Luan F.¹²,Carvalho Paulo S.³^ORCID,Gonçalves José E.¹,Diniz Renata²,Fernandes Christian¹^ORCID

Affiliation:

1. Laboratório de Controle de Qualidade de Medicamentos e Cosméticos, Departamento de Produtos Farmacêuticos, Faculdade de Farmácia, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, MG, Brazil

2. Departamento de Química, Instituto de Ciências Exatas (ICEx), Universidade Federal de Minas Gerais, 31270-901-Belo Horizonte, MG, Brazil

3. Instituto de Física, Universidade Federal do Mato Grosso do Sul, 79074-460, Campo Grande, MS, Brazil

Abstract

Three new metformin salts were prepared, allowing the optimization of the drug's pharmaceutical profile and diversifying the API solid-state landscape.

Funder

Fundação de Amparo à Pesquisa do Estado de Minas Gerais

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ00453D

Reference57 articles.

1. Pharmaceutical cocrystals, salts and multicomponent systems; intermolecular interactions and property based design