Two Novel Metformin Carboxylate Salts and the Accidental Discovery of Two 1,3,5-Triazine Antihyperglycemic Agent

Author:

An Qi1,Li Na2,Zhao Zhehui3,Wang Nuoqi2,Wang Xueying4,Yang Xiuying2,Yang Dezhi1ORCID,Zhang Li1ORCID,Lu Yang1ORCID,Du Guanhua2,Chan H. C. Stephen5

Affiliation:

1. Beijing City Key Laboratory of Polymorphic Drugs, Center of Pharmaceutical Polymorphs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P.R. China

2. Beijing City Key Laboratory of Drug Target and Screening Research, National Center for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P.R. China

3. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing Key Laboratory of Active Substances Discovery and Drugability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P.R. China

4. BayRay Innovation Center, Shenzhen Bay Laboratory, A2202, Gaoke Innovation Center, Guangqiao Road, Guangming District Shenzhen, Guangdong 518000, P.R. China

5. Shenzhen Zhongke Cedar Tree Trading Company, Shenzhen, Guangdong 518017, P.R. China

Funder

Government of Guangdong Province

Chinese Academy of Medical Sciences

National Natural Science Foundation of China

Pharmacopoeia Commission of the Ministry of Health of the People's Republic of China

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

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