Modified Kagan's amide: synthesis and application as a chiral solvating agent for hydrogen-bonding based chiral discrimination in NMR-Reference-Cited by-同舟云学术

Modified Kagan's amide: synthesis and application as a chiral solvating agent for hydrogen-bonding based chiral discrimination in NMR

Published:2015 Issue:57 Volume:5 Page:45943-45955
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jain Nilesh¹²³⁴⁵,Patel Ravi B.¹²³⁴⁵,Bedekar Ashutosh V.¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. M. S. University of Baroda

4. Vadodara 390 002

5. India

Abstract

A modified Kagan's amide, N-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethyl)-3,5-dinitrobenzamide has been designed, synthesized and screened as a Chiral Solvating Agent for discrimination of optically active substrates.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA06959A

Reference120 articles.

1. Incremental development of chiral selectors for underivatized profens

2. One-pot multi-substrate screening in asymmetric catalysis

3. Investigation of a New Family of Chiral Ligands for Enantioselective Catalysis via Parallel Synthesis and High-Throughput Screening

4. Polysaccharide-based chiral stationary phases for high-performance liquid chromatographic enantioseparation

5. A High-Throughput Screening Protocol for Fast Evaluation of Enantioselective Catalysts

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A simple protocol for determination of enantiopurity of amines using BINOL derivatives as chiral solvating agents via¹H- and ¹⁹F-NMR spectroscopic analysis;RSC Advances;2022

2. Spectroscopic Analysis: NMR and Shift Reagents;Reference Module in Chemistry, Molecular Sciences and Chemical Engineering;2022

3. Silver‐Mediated Conversion of Alcohols to Carbonates with Dialkylazodicarboxylate;ChemistrySelect;2021-12

4. Nuclear magnetic resonance chiral discrimination of fipronil and malathion agrochemicals: A case study;Chirality;2021-06-28

5. Asymmetric Synthesis of Merck’s Potent hNK1 Antagonist and Its Stereoisomers via Tandem Acylation/[3,3]-Rearrangement of 1,2-Oxazine N-Oxides;The Journal of Organic Chemistry;2020-08-11