New copper(i) complexes selective for prostate cancer cells-Reference-Cited by-同舟云学术

New copper(i) complexes selective for prostate cancer cells

Published:2020 Issue:35 Volume:49 Page:12273-12286
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Machado João Franco¹²³⁴⁵^ORCID,Sequeira Diogo⁶⁷⁸⁹¹⁰,Marques Fernanda¹¹¹²¹³¹⁴⁴^ORCID,Piedade M. Fátima M.¹⁵³⁴⁵¹⁶,Villa de Brito Maria J.¹²³⁴⁵,Helena Garcia M.¹²³⁴⁵,Fernandes Alexandra R.⁶⁷⁸⁹¹⁰^ORCID,Morais Tânia S.¹²³⁴⁵^ORCID

Affiliation:

1. CQE

2. Centro de Química Estrutural

3. Faculdade de Ciências

4. Universidade de Lisboa

5. 1749-016 Lisboa

6. UCIBIO

7. Departamento de Ciências da Vida

8. Faculdade de Ciências e Tecnologia

9. Universidade Nova de Lisboa

10. 2829-516 Caparica

11. C2TN

12. Centro de Ciências e Tecnologias Nucleares

13. Instituto Superior Técnico

14. Campus Tecnológico e Nuclear

15. Departamento de Química e Bioquímica

16. Portugal

Abstract

Synthesis of a new family of Cu(i)–phosphane complexes with N,O-heteroaromatic ligands leads to the complexes showing impressive cytotoxicity against LNCap human prostate cancer cells allied to high selectivity than against RWPE non-tumoral prostate cells.

Funder

Fundação para a Ciência e a Tecnologia

European Social Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/DT/D0DT02157A

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