Pelargonidin ameliorates CCl4-induced liver fibrosis by suppressing the ROS-NLRP3-IL-1β axis via activating the Nrf2 pathway-Reference-Cited by-同舟云学术

Pelargonidin ameliorates CCl4-induced liver fibrosis by suppressing the ROS-NLRP3-IL-1β axis via activating the Nrf2 pathway

Published:2020 Issue:6 Volume:11 Page:5156-5165
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Shi Yu-Sheng¹²³⁴⁵,Li Xiao-Xing⁶⁷⁸⁹^ORCID,Li Hao-Tian¹²³⁴⁵,Zhang Yan¹⁰¹¹¹²⁹^ORCID

Affiliation:

1. Key Laboratory of Biotechnology and Bioresources Utilization

2. Educational of Minister

3. College of Life Science

4. Dalian Nationalities University

5. Dalian 116600

6. School of Bioengineering

7. Dalian University of Technology

8. Dalian,116024

9. People's Republic of China

10. School of Traditional Chinese Medicine

11. Southern Medical University

12. Guangzhou 510515

Abstract

Liver fibrosis is a histological change that often occurs due to hepatic stellate cell (HSC) activation and excessive formation of an extracellular matrix in the liver.

Funder

Dalian Nationalities University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/FO/D0FO00660B

Reference40 articles.

1. The global burden of liver disease: a challenge for methods and for public health

2. Liver fibrogenesis and the role of hepatic stellate cells: New insights and prospects for therapy

3. Chronic liver injury, TGF-β, and cancer

4. Mechanisms of liver fibrosis resolution

5. Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

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