Association of cultured myotubes and fasting plasma metabolite profiles with mitochondrial dysfunction in type 2 diabetes subjects
Author:
Affiliation:
1. Bioprocess Technology Division
2. School of Industrial Technology
3. Universiti Sains Malaysia
4. 11800 Gelugor
5. Malaysia
6. Institute of Bioproduct Development
7. Universiti Teknologi Malaysia
8. 81310 Johor Bahru
Abstract
Discovering the predictive metabolomic markers for mitochondrial dysfunction in disease developments by utilizing both a cellular disease model (myotubes with mitochondrial dysfunction) and the fasting plasma of type 2 diabetes subjects.
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2017/MB/C7MB00333A
Reference62 articles.
1. International Diabetes Federation, IDF Diabetes Atlas, International Diabetes Federation, Brussels, Belgium, 7th edn, 2015
2. Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
3. Mitochondrial dysfunction as a central event for mechanisms underlying insulin resistance: the roles of long chain fatty acids
4. Mitochondrial and cellular mechanisms for managing lipid excess
5. Metabolomic Profiling Reveals Mitochondrial-Derived Lipid Biomarkers That Drive Obesity-Associated Inflammation
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