Synthesis of substituted 1,2-dihydroisoquinolines via Ni(ii) and Cu(i)/Ag(i) catalyzed double nucleophilic addition of arylamines to ortho-alkynyl donor–acceptor cyclopropanes (o-ADACs)
Author:
Affiliation:
1. Catalysis and Fine Chemicals Division
2. CSIR Indian Institute of Chemical Technology
3. Hyderabad – 500007
4. India
5. Academy of Scientific and Innovative Research (AcSIR)
Abstract
Synthesis of substituted 1,2-dihydroisoquinolines via double nucleophilic addition of primary arylamines to ortho-alkynyl donor–acceptor cyclopropanes (o-ADACs) in the presence of a catalytic Ni(ii) and Cu(i)/Ag(i) system has been developed.
Funder
Council of Scientific and Industrial Research, India
Science and Engineering Research Board
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00760B
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1. Functionalization of Sydnones with Donor‐Acceptor Cyclopropanes, Cyclobutanes, and Michael Acceptors
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3. A Mild Procedure for the Lewis Acid-Catalyzed Ring-Opening of Activated Cyclopropanes with Amine Nucleophiles
4. Synthesis of γ-(Arylamino)butyric Acid Derivatives via Ring-Opening Addition of Arylamines to Cyclopropane-1,1-Dicarboxylates
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