Reprogramming of arachidonic acid metabolism using α-terpineol to alleviate asthma: insights from metabolomics-Reference-Cited by-同舟云学术

Reprogramming of arachidonic acid metabolism using α-terpineol to alleviate asthma: insights from metabolomics

Published:2024 Issue:8 Volume:15 Page:4292-4309
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Rong Ying¹,Liu Fanglin¹,Zhou Hui¹,Yu Tong¹,Qin Zhaolong¹,Cao Qianwen¹,Liu Luyao¹,Ma Xiaoge¹,Qu Lingbo¹,Xu Peirong¹,Liao Xinglin²,Jiang Qiman²,Zhang Nan³,Xu Xia¹^ORCID

Affiliation:

1. Department of Medical Analysis, School of Pharmaceutical Science, Zhengzhou University, Zhengzhou, Henan, 450001, China

2. Nanyang LANHAISENYUAN Medical Technology Ltd, CO. Nanyang, Henan, 473000, China

3. Department of Pharmaceutics, School of Pharmaceutical Science, Zhengzhou University, Zhengzhou, Henan, 450001, China

Abstract

α-Terpineol and Hp-β-CD were prepared for Ter-Hp-β-CD inclusion complex for nebulized inhalation treatment in asthmatic mice. Biochemical indices and differential metabolite assays in mice showed that α-Terpineol is a potential drug to prevent asthma by reprogramming arachidonic acid metabolism.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D3FO04078J

Reference53 articles.

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