The absorption, distribution, metabolism and excretion of procyanidins

Author:

Zhang Liang1234,Wang Yijun1234,Li Daxiang1234,Ho Chi-Tang5678,Li Junsong910114,Wan Xiaochun1234

Affiliation:

1. State Key Laboratory of Tea Plant Biology and Utilization

2. Anhui Agricultural University

3. Hefei 230036

4. China

5. Department of Food Science

6. Rutgers University

7. New Brunswick

8. USA

9. College of Pharmacy

10. Nanjing University of Chinese Medicine

11. Nanjing 210023

Abstract

This review summarizes research on thein vivoandin vitroADME of procyanidins (PAs), including the degradation of PAs in gastric digestion, their absorption in the small intestine and the pathway of their metabolism by colonic microflora. A systematic comparative analysis of published data is performed to elucidate the pharmacokinetics of PAsin vivo.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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