His18 promotes reactive oxidative stress production in copper-ion mediated human islet amyloid polypeptide aggregation
Author:
Affiliation:
1. School of Physics Science and Technology
2. Ningbo University
3. China
4. Shanghai Advanced Research Institute
5. Chinese Academy of Sciences
6. Single Molecule Study Laboratory
7. College of Engineering
8. University of Georgia
9. Athens
10. USA
Abstract
His18 promotes H2O2 production in copper-ion mediated hIAPP aggregation.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Ningbo
Ningbo University
Natural Science Foundation of Zhejiang Province
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA09943C
Reference41 articles.
1. Unfolding the role of protein misfolding in neurodegenerative diseases
2. Implications of peptide assemblies in amyloid diseases
3. Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils
4. Metal Ions and Intrinsically Disordered Proteins and Peptides: From Cu/Zn Amyloid-β to General Principles
5. Islet Amyloid: A Critical Entity in the Pathogenesis of Type 2 Diabetes
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