Synthesis and in vitro study of novel borneol derivatives as potent inhibitors of the influenza A virus-Reference-Cited by-同舟云学术

Synthesis and in vitro study of novel borneol derivatives as potent inhibitors of the influenza A virus

Published:2017 Issue:5 Volume:8 Page:960-963
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Sokolova A. S.¹²³⁴⁵^ORCID,Yarovaya O. I.¹²³⁴⁵,Semenova M. D.¹²³⁴,Shtro A. A.⁶⁷⁸⁴,Orshanskaya I. R.⁶⁷⁸⁴,Zarubaev V. V.⁶⁷⁸⁴,Salakhutdinov N. F.¹²³⁴⁵

Affiliation:

1. Novosibirsk Institute of Organic Chemistry

2. Siberian Branch of the Russian Academy of Sciences

3. 630090 Novosibirsk

4. Russia

5. Novosibirsk State University

6. Laboratory of Chemotherapy

7. Influenza Research Institute

8. 197376 St. Petersburg

Abstract

Herein, we present the design and synthesis of a series of novel heterocyclic derivatives of (−)-borneol and (−)-isoborneol as potent inhibitors of the influenza A virus.

Funder

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MD/C6MD00657D

Reference25 articles.

1. Adamantane Resistance Among Influenza A Viruses Isolated Early During the 2005-2006 Influenza Season in the United States

2. Surveillance of Resistance to Adamantanes among Influenza A(H3N2) and A(H1N1) Viruses Isolated Worldwide

3. Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans

4. Infections With Oseltamivir-Resistant Influenza A(H1N1) Virus in the United States

5. Global Transmission of Oseltamivir-Resistant Influenza

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