Insecticidal activity of isoborneol derivatives against Musca domestica adults and Culex quinquefasciatus larvae

Abstract

Musca domestica L., a common housefly, and Culex quinquefasciatus mosquito are quite well-known pests that can transfer a wide range of diseases to humans as well as animals. In this study, various isoborneol derivatives including esters, ethers and thioethers were synthesized fromisoborneol under mild conditions. These derivatives were evaluated for inhibition of house-fly M. domestica adults and Cx. quinquefasciatus larvae. Two of the synthesized isoborneol ester derivatives (2 and 3) showed good activity against both insect species. Additional two derivatives (6 and 9) were active against M.domestica L. and the derivatives (1–3, 8) were active against Cx. quinquefasciatus larvae.