A simple route towards the synthesis of 1,4,5-trisubstituted 1,2,3-triazoles from primary amines and 1,3-dicarbonyl compounds under metal-free conditions
Author:
Affiliation:
1. Key Laboratory of Interfacial Reaction & Sensing Analysis in Universities of Shandong
2. School of Chemistry and Chemical Engineering
3. University of Jinan
4. Jinan
5. P. R. China
Abstract
A metal-free protocol for the synthesis of fully substituted 1,2,3-triazoles in a one-step reaction from easily available primary amines, 1,3-dicarbonyl compounds and tosyl azide was developed under air.
Funder
Natural Science Foundation of Shandong Province
University of Jinan
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB01156K
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