Revealing the ACE receptor binding properties and interaction mechanisms of salty oligopeptides from Stropharia rugosoannulata mushroom by molecular simulation and antihypertensive evaluation

Author:

Li Wen123ORCID,Chen Wanchao12,Wang Jinbin4,Zhang Zhong12,Wu Di12,Liu Peng12,Li Zhengpeng12ORCID,Ma Haile3,Yang Yan12

Affiliation:

1. Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Engineering Research Center of Edible Fungi, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, People's Republic of China

2. Shanghai Guosen Bio-tech Co. Ltd, Shanghai 201403, China

3. School of Food & Biological Engineering, Institute of Food Physical Processing, Jiangsu University, Zhenjiang 212013, China

4. Institute of Biotechnology Research, Shanghai Academy of Agricultural Sciences, Key Laboratory of Agricultural Genetics and Breeding, Shanghai 201106, China

Abstract

The salty oligopeptides from Stropharia rugosoannulata have been proven to be potential ACE inhibitors.

Funder

Natural Science Foundation of Shanghai

Publisher

Royal Society of Chemistry (RSC)

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