Re-engineering natural products to engage new biological targets-Reference-Cited by-同舟云学术

Re-engineering natural products to engage new biological targets

Published:2020 Issue:11 Volume:37 Page:1395-1403
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Motika Stephen E.¹²³⁴⁵,Hergenrother Paul J.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Institute for Genomic Biology

3. Cancer Center at Illinois

4. University of Illinois

5. Urbana-Champaign

Abstract

Incorporating natural product-like features within small-molecule screening collections is of great interest. We highlight an emerging strategy that achieves this goal by using abundant natural products as starting points for compound construction.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NP/D0NP00059K

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