Synthetic studies of callyspongiolide: synthesis of the macrolactone core of the molecule-Reference-Cited by-同舟云学术

Synthetic studies of callyspongiolide: synthesis of the macrolactone core of the molecule

Published:2016 Issue:28 Volume:14 Page:6769-6779
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Athe Sudhakar¹²³⁴,Sharma Ashish¹²³⁴,Marumudi Kanakaraju⁵²³⁴,Ghosh Subhash¹²³⁴

Affiliation:

1. Organic and Biomolecular Chemistry Division

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad 500007

4. India

5. Centre for NMR & Structural Chemistry

Abstract

Synthesis of the fully functionalized macrolactone core of the highly cytotoxic marine natural product callyspongiolide has been achievedviaaZ-selective intramolecular H–W–E reaction and allylic alkylation of an activatedZ-allylic alcoholviaan S_N2′ fashion as key steps.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01007E

Reference37 articles.

1. Drug development from marine natural products

2. Marine-Sourced Anti-Cancer and Cancer Pain Control Agents in Clinical and Late Preclinical Development

3. Callyspongiolide, a Cytotoxic Macrolide from the Marine Sponge Callyspongia sp.

4. Kahalalide Derivatives from the Indian Sacoglossan Mollusk Elysia grandifolia

5. Asymmetric alkylation reactions of chiral imide enolates. A practical approach to the enantioselective synthesis of .alpha.-substituted carboxylic acid derivatives

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Origin of the selectivity in the ring-closing metathesis step of the synthesis of (−)-callyspongiolide: Formation of fourteen-versus eight-membered rings;Tetrahedron;2022-10

2. Total synthesis of the proposed structure of metacridamide B;Tetrahedron Letters;2021-10

3. Total Synthesis of Thiocladospolide A and Its C2-Epimer;Synthesis;2021-09-23

4. Stereoselective Synthesis of the C19–C39 Fragment of Bastimolide A;SynOpen;2021-09-17

5. The Synthesis and Bioactivity of the Marine Macrolide Callyspongiolide;Chemistry – A European Journal;2020-12-14