The origin of experimental regioselectivity in ring-closing reaction of pyrido[1,2-e]purine systems and comparison of the aromaticity character of probable products: a mechanistic study based on DFT insights

Author:

Moghimi Parvin1ORCID,Bolourian Shadi2,Shiri Ali1ORCID,Eshghi Hossein1ORCID,Hosseini Fereshteh2,Sabet-Sarvestani Hossein2ORCID

Affiliation:

1. Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran

2. Department of Food Additives, Food Science and Technology Research Institute, Research Center for Iranian Academic Center for Education, Culture and Research (ACECR), Khorasan Razavi Branch, Mashhad, Iran

Abstract

Investigation of the regioselectivity, mechanistic aspects and aromaticity character of hydrazine derivatives of pyrido[1,2-e]purine in a ring-closing reaction is the main purpose of this study.

Funder

Academic Center for Education, Culture and Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Reference68 articles.

1. V. I.Minkin , M. N.Glukhovtsev and B. Y.Simkin , Aromaticity and antiaromaticity , John Wiley & Sons , Incorporated, 1994

2. J.Cornelisse , Aromaticity and Antiaromaticity. Electronic and Structural Aspects V.I. Minkin, M.N. Glukhovtsev and B.Ya. Simkin John Wiley & Sons, Inc., New York, 1994 313 pp., £66.00 ISBN 0-471-59382-6, 1995

3. Unusual reactivity of small cyclophanes: nucleophilic attack on 11-chloro- and 8,11-dichloro[5]metacyclophane

4. What is aromaticity?

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