Synthesis of pyrido[1,2-a]indol-6(7H)-ones via a visible light-photocatalyzed formal (4 + 2) cycloaddition of indole-derived bromides and alkenes or alkynes-Reference-Cited by-同舟云学术

Synthesis of pyrido[1,2-a]indol-6(7H)-ones via a visible light-photocatalyzed formal (4 + 2) cycloaddition of indole-derived bromides and alkenes or alkynes

Published:2023 Issue:6 Volume:25 Page:2453-2457
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Wei Minghui¹,Liu Chengkou¹,Wang Chang-Sheng¹,Li Yuguang²,Qiu Peng³,Dong Quanxiao³,Yang Zhao⁴,Fang Zheng¹^ORCID,Guo Kai¹⁵^ORCID

Affiliation:

1. College of Biotechnology and Pharmaceutical Engineering Nanjing Tech University, 30 Puzhu Rd S., Nanjing, 211816, China

2. Biology and Medicine Department, Jiangsu Industrial Technology Research Institute, Nanjing 210031, P.R. China

3. Hebei Tieke Yichen New Materials Technology Co., Ltd., Shijiazhuang, Hebei 052160, China

4. College of Engineering, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210003, China

5. State Key Laboratory of Materials-Oriented Chemical Engineering, 30 Puzhu Rd S., Nanjing, 211816, China

Abstract

We successfully developed an unprecedented synthesis route to pyrido[1,2-a]indol-6(7H)-ones through a visible light-photocatalyzed formal (4 + 2) cycloaddition of indole-derived bromides and alkenes or alkynes in a microchannel reactor.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/GC/D2GC04491A

Reference41 articles.

1. Alkylation of phenylglycinol-derived bicyclic lactams. Enantioselective synthesis of 3-alkylpiperidines

2. Eburnamine derivatives and the brain

3. Organocatalytic strategies for the asymmetric functionalization of indoles

4. Gold Approaches to Polycyclic Indole Alkaloids

5. Intramolecular Dearomative Oxidative Coupling of Indoles: A Unified Strategy for the Total Synthesis of Indoline Alkaloids

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