Unorthodox cascade reaction of arynes and N-nitrosamides leading to indazole scaffolds-Reference-Cited by-同舟云学术

Unorthodox cascade reaction of arynes and N-nitrosamides leading to indazole scaffolds

Published:2022 Issue:8 Volume:58 Page:1187-1190
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Sureshbabu Popuri¹,Bhajammanavar Vinod¹,Choutipalli Venkata Surya Kumar²^ORCID,Subramanian Venkatesan²^ORCID,Baidya Mahiuddin¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Madras, Chennai 600 036, Tamil Nadu, India

2. Inorganic and Physical Chemistry Laboratory, CSIR-Central Leather Research Institute, Chennai 600 020, Tamil Nadu, India

Abstract

A cascade annulation of arynes with N-alkyl-N-nitrosamides is developed by leveraging aryne σ-insertion and C(sp3)–H bond functionalization strategies under transition-metal-free conditions to access indazoles in high yields and regioselectivity.

Funder

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D1CC05655G

Reference33 articles.

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3. Arynes and Cyclohexyne in Natural Product Synthesis

4. Transition-Metal-Free Multicomponent Reactions Involving Arynes, N-Heterocycles, and Isatins

5. FLUORIDE-INDUCED 1,2-ELIMINATION OFO-TRIMETHYLSILYLPHENYL TRIFLATE TO BENZYNE UNDER MILD CONDITIONS

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