On the investigation of hybrid quinones: synthesis, electrochemical studies and evaluation of trypanocidal activity-Reference-Cited by-同舟云学术

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On the investigation of hybrid quinones: synthesis, electrochemical studies and evaluation of trypanocidal activity

Published:2015 Issue:95 Volume:5 Page:78047-78060
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jardim Guilherme A. M.¹²³⁴⁵,Reis Wallace J.¹²³⁴⁵,Ribeiro Matheus F.¹²³⁴⁵,Ottoni Flaviano M.⁶³⁴⁵,Alves Ricardo J.⁶³⁴⁵,Silva Thaissa L.⁷⁸⁹⁵,Goulart Marilia O. F.⁷⁸⁹⁵,Braga Antonio L.²¹⁰¹¹⁵^ORCID,Menna-Barreto Rubem F. S.¹²¹³¹⁴¹⁵⁵,Salomão Kelly¹²¹³¹⁴¹⁵⁵,de Castro Solange L.¹²¹³¹⁴¹⁵⁵,da Silva Júnior Eufrânio N.¹²³⁴⁵

Affiliation:

1. Institute of Exact Sciences

2. Department of Chemistry

3. UFMG

4. Belo Horizonte

5. Brazil

6. School of Pharmacy

7. Institute of Chemistry and Biotechnology

8. UFAL

9. Maceió

10. UFSC

11. Florianópolis

12. Laboratory of Cellular Biology

13. IOC

14. FIOCRUZ

15. Rio de Janeiro

Abstract

Thirty-eight compounds were evaluated against T. cruzi and six were found to be more potent against trypomastigotes than benznidazole.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA16213K

Reference87 articles.

1. American Trypanosomiasis (Chagas Disease)

2. Characterization of Trypanosoma cruzi isolated from humans, vectors, and animal reservoirs following an outbreak of acute human Chagas disease in Santa Catarina State, Brazil

3. Mecanismos alternativos de transmissão do Trypanosoma cruzi no Brasil e sugestões para sua prevenção

4. Epidemiology, control and surveillance of Chagas disease: 100 years after its discovery

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