A Brønsted acid catalyzed tandem reaction for the diastereoselective synthesis of cyclobuta-fused tetrahydroquinoline carboxylic esters-Reference-Cited by-同舟云学术

A Brønsted acid catalyzed tandem reaction for the diastereoselective synthesis of cyclobuta-fused tetrahydroquinoline carboxylic esters

Published:2021 Issue:41 Volume:19 Page:8912-8916
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Marras Valentina¹,Caboni Pierluigi²^ORCID,Secci Francesco¹^ORCID,Guillot Régis³^ORCID,Aitken David J.³^ORCID,Frongia Angelo¹^ORCID

Affiliation:

1. Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, Complesso Universitario di Monserrato, S.S. 554, Bivio per Sestu, I-09042, Monserrato, Cagliari, Italy

2. Dipartimento di Scienze della Vita e dell'Ambiente, Università degli Studi di Cagliari, Via Ospedale 72, 09124, Cagliari, Italy

3. Université Paris Saclay, CNRS, ICMMO, CP3A Organic Synthesis Group & Services Communs, 420 rue du Doyen Georges Poitou, 91405 Orsay cedex, France

Abstract

We have established a Brønsted acid catalyzed diastereoselective synthesis of diversely substituted cyclobuta-fused tetrahydroquinoline carboxylic esters through a new tandem aza-Michael addition-aza-Friedel–Crafts cyclization process.

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Regione Autonoma della Sardegna

Fondazione Banco di Sardegna

Università degli Studi di Cagliari

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01518D

Reference44 articles.