Substrate-dependent regiodivergence in [3 + 2] annulation reactions of 2-(phenacylethylidene)cyclobutanones with thioureas

Author:

Barranco Stefano1ORCID,Pagnanini Alessio1ORCID,Cuccu Federico1,Caboni Pierluigi2ORCID,Guillot Régis3ORCID,Aitken David J.3ORCID,Frongia Angelo1ORCID

Affiliation:

1. Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, Complesso Universitario di Monserrato, S.S. 554, Bivio per Sestu, I-09042, Monserrato, Cagliari, Italy

2. Dipartimento di Scienze della Vita e dell'Ambiente, Università degli Studi di Cagliari, Complesso Universitario di Monserrato-Blocco A, S.S. 554, Bivio per Sestu, I-09042, Monserrato, Cagliari, Italy

3. Université Paris-Saclay, CNRS, ICMMO, 17 Avenue des Sciences, 91400 Orsay, France

Abstract

We report here a successful synthesis of previously unknown cyclobutane-fused imidazolidine-2-thione and thiazolidine-2-imine derivatives in good to high yields.

Publisher

Royal Society of Chemistry (RSC)

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