Viewing 3D spatial biology with highly-multiplexed Raman imaging: from spectroscopy to biotechnology

Author:

Li Yingying1,Sun Yuchen1,Shi Lixue1ORCID

Affiliation:

1. Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, and Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China

Abstract

Ultra-sensitive Raman imaging is an emerging platform for detecting biomarkers with scalable multiplexity. We review recent advances in highly-multiplexed Raman imaging and how they contribute to the technology revolution in 3D spatial biology.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

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