Novel salts and cocrystals of the antifolate drug trimethoprim and their role in the enhancement of solubility and dissolution-Reference-Cited by-同舟云学术

Novel salts and cocrystals of the antifolate drug trimethoprim and their role in the enhancement of solubility and dissolution

Published:2023 Issue:8 Volume:25 Page:1220-1231
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Surampudi Anuja Venkata Sai Durga¹²,Ramakrishna Sistla³²,Pallavi Alegete⁴,Balasubramanian Sridhar¹²^ORCID

Affiliation:

1. Centre for X-ray Crystallography, Department of Analytical & Structural Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Uppal Road, Hyderabad-500007, Telangana, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India

3. Applied Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Uppal Road, Hyderabad-500007, Telangana, India

4. Department of Analytical & Structural Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Uppal Road, Hyderabad-500007, Telangana, India

Abstract

Trimethoprim (TMP) is a BCS class II anti-folate drug with poor aqueous solubility.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CE/D2CE01436J

Reference57 articles.

1. Cocrystallization of Trimethoprim and Solubility Enhancement via Salt Formation

2. Studies on trimethoprim:hydroxypropyl-β-cyclodextrin: aggregate and complex formation

3. Tetramorphs of the Antibiotic Drug Trimethoprim: Characterization and Stability