Cocrystallization of Trimethoprim and Solubility Enhancement via Salt Formation
Author:
Affiliation:
1. Department of Chemistry and Biochemistry, Texas Tech University, 1204 Boston Avenue, Lubbock, Texas 79409, United States
Funder
Texas Tech University
Publisher
American Chemical Society (ACS)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.cgd.0c01197
Reference36 articles.
1. Solubility of Pharmaceutical Solids
2. Vibrational spectroscopic and DFT study of trimethoprim
3. Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase
4. World Health Organization. Executive Summary: The Selection and Use of Essential Medicines 2019. Report of the 22nd WHO Expert Committee on the Selection and Use of Essential Medicines: WHO Headquarters: Geneva, April 1–5, 2019; World Health Organization, 2019.
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