Cocrystallization of Trimethoprim and Solubility Enhancement via Salt Formation

Author:

Zheng Qixuan1ORCID,Unruh Daniel K.1ORCID,Hutchins Kristin M.1ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, Texas Tech University, 1204 Boston Avenue, Lubbock, Texas 79409, United States

Funder

Texas Tech University

Publisher

American Chemical Society (ACS)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Reference36 articles.

1. Solubility of Pharmaceutical Solids

2. Vibrational spectroscopic and DFT study of trimethoprim

3. Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase

4. World Health Organization. Executive Summary: The Selection and Use of Essential Medicines 2019. Report of the 22nd WHO Expert Committee on the Selection and Use of Essential Medicines: WHO Headquarters: Geneva, April 1–5, 2019; World Health Organization, 2019.

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