Synthesis, characterization and biological evaluation of labile intercalative ruthenium(ii) complexes for anticancer drug screening-Reference-Cited by-同舟云学术

Synthesis, characterization and biological evaluation of labile intercalative ruthenium(ii) complexes for anticancer drug screening

Published:2016 Issue:33 Volume:45 Page:13135-13145
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Huang Huaiyi¹²³⁴⁵,Zhang Pingyu¹²³⁴⁵,Chen Yu¹²³⁴⁵,Qiu Kangqiang¹²³⁴⁵,Jin Chengzhi¹²³⁴⁵,Ji Liangnian¹²³⁴⁵,Chao Hui¹²³⁴⁵

Affiliation:

1. MOE Key Laboratory of Bioinorganic and Synthetic Chemistry

2. School of Chemistry and Chemical Engineering

3. Sun Yat-Sen University

4. Guangzhou 510275

5. P. R. China

Abstract

[Ru(tpy)(N^N)Cl]⁺ were synthesized for anticancer evolution. Ru2–Ru4 were dual-mode DNA-binding complexes and exhibited higher DNA binding affinity, better cellular uptake efficiency and higher anticancer activity than Ru1.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/DT/C6DT01270A

Reference98 articles.

1. Global cancer statistics

2. European cancer mortality predictions for the year 2015: does lung cancer have the highest death rate in EU women?

3. Non-Platinum Chemotherapeutic Metallopharmaceuticals

4. New Principles in Medicinal Organometallic Chemistry

5. Interactions of Antitumor Metallodrugs with Serum Proteins: Advances in Characterization Using Modern Analytical Methodology

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