Enantioselective synthesis of 2-amino-4<i>H</i>-chromene derivatives with antifungal activities on phytopathogenic fungi-Reference-Cited by-同舟云学术

Enantioselective synthesis of 2-amino-4H-chromene derivatives with antifungal activities on phytopathogenic fungi

Published:2024 Issue:13 Volume:11 Page:3692-3699
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhang Man¹,Ru Yifan¹,Wang Shilin¹,Fu Wen¹,Li Tianyu¹,Shao Xusheng¹^ORCID,Li Zhong¹,Yang Wu-Lin¹^ORCID

Affiliation:

1. Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China

Abstract

An Ir-catalyzed enantioselective cascade allylation/cyclization reaction of 2-(1-hydroxyallyl)phenols was developed, affording antifungal 2-amino-4H-chromene derivatives with good to excellent enantioselectivities.

Funder

National Natural Science Foundation of China

Shanghai Rising-Star Program

Natural Science Foundation of Shanghai Municipality

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00686K

Reference76 articles.

1. Enantioselective Organocatalyzed Synthesis of 2-Amino-3-cyano-4H-chromene Derivatives

2. Catalytic Asymmetric Syntheses of 2‐Aryl Chromenes

3. Advancements in the Preparation of 4H‐Chromenes: An Overview

4. Antivascular and antitumor evaluation of 2-amino-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-4H-chromenes, a novel series of anticancer agents

5. Discovery of 4-Aryl-4H-Chromenes as Potent Apoptosis Inducers Using a Cell- and Caspase-Based Anti-Cancer Screening Apoptosis Program (ASAP): SAR Studies and the Identification of Novel Vascular Disrupting Agents