Novel mono-lipidated dimeric glucagon-like peptide-1 receptor agonist with improved long-acting and hypoglycemic activity-Reference-Cited by-同舟云学术

Novel mono-lipidated dimeric glucagon-like peptide-1 receptor agonist with improved long-acting and hypoglycemic activity

Author:

Sun Lidan¹²³⁴⁵^ORCID,Han Jing⁶⁷⁸⁹⁵^ORCID,Chen Xinyu⁶⁷⁸⁹⁵,Han Yue⁶⁷⁸⁹⁵,Wu Lingling¹²³⁴⁵,E Xia¹²³⁴⁵

Affiliation:

1. Integrated Medicine Research Center for Neurological Rehabilitation

2. College of Medicine

3. Jiaxing University

4. Jiaxing 314001

5. PR China

6. School of Chemistry and Chemical Engineering

7. Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials

8. Jiangsu Normal University

9. Xuzhou 221116

Abstract

Dimerization and lipidation were effectively applied to GLP-1 to make Lip-Di-GLP-1 as a long-acting antidiabetic agent.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

Reference22 articles.

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