Rational design and biological evaluation of gemfibrozil modified Xenopus GLP-1 derivatives as long-acting hypoglycemic agents-Reference-Cited by-同舟云学术

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Rational design and biological evaluation of gemfibrozil modified Xenopus GLP-1 derivatives as long-acting hypoglycemic agents

Published:2020-07 Issue: Volume:198 Page:112389
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Han Jing,Fu Junjie,Yang Qimeng,Zhou Feng,Chen Xinyu,Li Chenglin,Yin Jian

Funder

National Natural Science Foundation of China

Central

National First-class Discipline Program of Light Industry Technology and Engineering

Natural Science Foundation of Xuzhou

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference47 articles.

1. Ethanolic Ginkgo biloba leaf extract prevents renal fibrosis through Akt/mTOR signaling in diabetic nephropathy;Lu;Phytomedicine,2015

2. Quercetin inhibits the mTORC1/p70S6K signaling-mediated renal tubular epithelial–mesenchymal transition and renal fibrosis in diabetic nephropathy;Lu;Pharmacol. Res.,2015

3. Mangiferin attenuates renal fibrosis through down-regulation of osteopontin in diabetic rats;Zhu;Phytother Res.,2015

4. Enhancement of glyoxalase 1, a polyfunctional defense enzyme, by quercetin in the brain in streptozotocin-induced diabetic rats;Zhu;N-S. Arch. Pharmacol.,2018

5. A variant of GRK5 is associated with the therapeutic efficacy of repaglinide in Chinese Han patients with type 2 diabetes mellitus;Shang;Drug Dev. Res.,2018

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1. Research advances in peptide‒drug conjugates;Acta Pharmaceutica Sinica B;2023-09

2. Peptide–drug conjugates (PDCs): a novel trend of research and development on targeted therapy, hype or hope?;Acta Pharmaceutica Sinica B;2023-02

3. Peptide-based long-acting co-agonists of GLP-1 and cholecystokinin 1 receptors as novel anti-diabesity agents;European Journal of Medicinal Chemistry;2022-04

4. Strengthening Semaglutide-GLP-1R Binding Affinity via a Val27-Arg28 Exchange in the Peptide Backbone of Semaglutide: A Computational Structural Approach;Journal of Computational Biophysics and Chemistry;2021-07-26

5. Stapled, Long-Acting Xenopus GLP-1-Based Dual GLP-1/Glucagon Receptor Agonists with Potent Therapeutic Efficacy for Metabolic Disease;Molecular Pharmaceutics;2021-07-09

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