Sensitive detection of p53 DNA based on spatially confined fluorescence resonance energy transfer and multivalent assembly of branched DNA-Reference-Cited by-同舟云学术

Sensitive detection of p53 DNA based on spatially confined fluorescence resonance energy transfer and multivalent assembly of branched DNA

Published:2021 Issue:37 Volume:13 Page:4314-4319
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Liu Yeling¹,Sun Xia¹,Yuan Hui¹,Liu Bingxin¹,Zhou Bingqian¹,Chen Xuening²,Li Xia¹^ORCID,Xue Qingwang¹^ORCID

Affiliation:

1. Department of Chemistry, Liaocheng University, Liaocheng 252059, China

2. College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, China

Abstract

We present a spatially confined FRET (SC-FRET) probe with a stable structure and strong signal output, consisting of multivalent FRET pairs labeled with FAM or TAMRA.

Funder

Natural Science Foundation of Shandong Province

Department of Education of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AY/D1AY01110C

Reference40 articles.

1. Enhanced Suppression of a Protein–Protein Interaction in Cells Using Small-Molecule Covalent Inhibitors Based on an N-Acyl-N-alkyl Sulfonamide Warhead

2. Prion-like p53 Amyloids in Cancer

3. Nicotine Promotes WRL68 Cells Proliferation Due to the Mutant p53 Gain-of-Function by Activating CDK6-p53-RS-PIN1-STAT1 Signaling Pathway

4. Three-Dimensional DNA Nanomachine Biosensor by Integrating DNA Walker and Rolling Machine Cascade Amplification for Ultrasensitive Detection of Cancer-Related Gene

5. Direct LC-MS/MS Detection of Guanine Oxidations in Exon 7 of the p53 Tumor Suppressor Gene

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